
Heather O'Sullivan
MSN, APRN
President and Chief Operating Officer, Healthcare at Home
Mass General Brigham
Heather O’Sullivan is President and Chief Operating Officer of Healthcare at Home for Mass General Brigham, where she leads the strategic direction, operations, and growth of home-based acute, post-acute, and palliative care. She launched and scaled the nation’s largest hospital-at-home program, delivering over 6,000 acute episodes and unlocking more than 30,000 inpatient bed days in under three years, all while achieving superior clinical outcomes and zero unexpected mortality. With over two decades of leadership across payer and provider sectors; including roles at Cardinal Health, UnitedHealth Group, and Humana, Dr. O’Sullivan is a recognized innovator in healthcare transformation. She was named a 2023 Top Innovator by Modern Healthcare and a 2024 honoree among the Top 100 Women-Led Businesses in Massachusetts by The Women’s Edge and The Boston Globe. She plays a national advocacy role in shaping regulatory pathways for care-at-home delivery and serves as a guest speaker at Harvard University and faculty at the MGH Institute of Health Professions. She is a board member of the Home Care Alliance of Massachusetts and an advisor to Cairns Health. Dr. O’Sullivan holds a BSN from the Medical University of South Carolina and an MSN from Simmons University, and spent much of her clinical career as a nurse practitioner in long-term care.




